I respect Joe Rogan as a thinker, and he raises a great point:
It is possible that this cultural fascination with mystery has propagated the Sasquatch myth. If Sasquatch is not real or extinct then the mystery will continue indefinitely since proving absolutely that Sasquatch does not exist is essentially impossible. This idea is probably responsible for the popularity of ghosts, aliens, and other cryptids. Although it should be acknowledged that the physical evidence for Sasquatch is relatively greater.